BIOFILM FORMATION AND ANTIMICROBIAL RESISTANCE IN ISOLATES OF PSEUDOMONAS AERUGINOSA FROM BENUE STATE UNIVERSITY TEACHING HOSPITAL MAKURDI, NIGERIA
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
Pseudomonas aeruginosa is one of the biofilm-forming bacteria implicated in infections such as, urinary tract infections, medical device infections, middle ear infections, cystic fibrosis, wounds etc. that pose serious threat to patients, resulting in prolong hospital stay, morbidity and high mortality, with ultimate economic burden and retardation of antibiotics effectiveness. This study determined the biofilm production potential and antimicrobial resistance pattern in isolates of Pseudomonas aeruginosa from Benue State University Teaching HospitalMakurdi, Nigeria. All suspected Pseudomonas aeruginosa isolates from samples submitted to the Medical Microbiology Laboratory Unit of the Hospital within a period of six (6) months from August, 2013 to January 2014, were collected, purified and identified using standard microbiological techniques. The distribution of Pseudomonas aeruginosa isolates (n-81) confirmed were 32(39.51%) from ear swab, 24(29.63%) from urine, 17(20.98%) wound swab, and 8(9.88%). Majority of the isolates 54 (67%) were biofilm positive. The prevalence of biofilm production by Pseudomonas aeruginosa isolates in the different samples evaluated were as follows: 44.4% (ear swab), 27.8% (wound swab), 18.5% (urine) and 9.9%(blood). Pseudomonas aeruginosa isolates evaluated in this study were resistant to the antipseudomonad agents: 73% to TicarcillinClavulanic acid; 32% to Ceftazidine; 28% to Ciprofloxacin; 26% to Amikacin; 20% to Gentamicin; and 1 % to Imipenem. Statistical analysis showed that there was no significant difference in antibiotics resistance pattern of biofilm producers and non-biofilm producing Pseudomonas aeruginosa isolates. In this study, 36 (44.4%) of the isolates were multidrug resistant (MDR). Resistance to Ciprofloxacin, an indicator antibiotic for multi-drug resistant (MDR) isolates was twenty eight percent (28%). Screening for quinolone resistant gene qnr in the study showed that 4(21.1%) carriedqnrB quinolone resistant genes.
Related Project Materials
INFLUENCE OF SOCIO ECONOMIC BACKGROUND ON SECONDARY SCHOOL STUDENT PERCEPTION OF THEIR SCHOOL LEARNING ENVIRONMENT IN CALABAR MUNICIPALITY, CROSS RIVER STATE
Background to the study
Socio-economic background or status refers to a person’s position in a gi...
PERCEPTION OF STUDENTS IN TEACHING AND LEARNING OF MATHEMATICS
Abstract
The research sought to find out the perception of students towards Mathematics and how it affects their academic attainment in a...
THE PROBLEMS AND PROSPECT OF MANAGEMENT OF STUDENTS HOSTEL ACCOMMODATION IN HIGHER INSTITUTION IN NIGERIA
ABSTRACT
Problems and prospects of student hostile Accommodation problem in IMT, is the topic of this write-up. Th...
CREDIT MANAGEMENT, CREDIT POLICY AND THE PERFORMING OF BANK IN AKURE, ONDO STATE NIGERIA
BACKGROUND OF THE STUDY
Credit is one of the many factors that can be used by a firm to influence...
ARTHRITIS AND THE HEALTH OF THE AGED
ABSRACT
Work disability—a common outcome of rheumatoid arthritis (RA)—is a societal (for example, financial...
A CRITICAL REVIEW OF TEACHERS’ QUALIFICATION AND SCHOOL ENVIRONMENT; ITS IMPACT ON JUNIOR STUDENT PERFORMANCE IN BASIC SCIENCE
Statement of the Problem
There are contemporary problems in the teaching and learning of Integrated Sci...
OWNERSHIP STRUCTURE AND IITS IMPACT ON DIVIDEND POLICY OF LISTED DEPOSIT MONEY BANKS IN NIGERIA
EXCERPT FROM THE STUDY
Adeiza, Kabiru, and Muhibudeen (2015) utilized the variables in the listed chemical and paint fir...
THE EVALUATION OF DISTRIBUTION CHANNEL OF PETROLEUM PRODUCTS (CASE STUDY MOBIL)
ABSTRACT
The present study -was set to investigate the impact of advertising on the consumer buying decision. The st...
RELIABILITY-BASED ANALYSIS OF COMPOSITE SOLID SLENDER TIMBER COLUMNS WITH ALUMINIUM LAMINATES USING SELECTED NIGERIAN TIMBER SPECIES
ABSTRACT
Four timber species (Strombosia pustulata, Macrocarpa biquertii, Entandrophragma cylindricum and Nauclea diderichii) were lamina...
THE OBSTACLES AFFECTING THE SECONDARY EDUCATION STANDARD IN NIGERIA
ABSTRACT
This research work was carried out to investigate into the obstacles affecting the secondary education standard...
